Tag: ai
rarelens: building a rare-disease variant triage platform, and the four things I got wrong
An end-to-end rare-disease variant triage platform: a Nextflow pipeline, three execution backends behind one API call, Terraform for two cloud tracks, and a phenotype-driven ranking measured against 10,178 published cases. Including the model metric that collapsed to exactly random once I removed the feature doing all the work.
The Programmer’s Fulcrum 11 September, 2026
This post originally appeared on The Fulcrum. Welcome to this week's The Programmer's Fulcrum. It's your weekly curation of the essential news in the Open Media Network and Open Social development communities with a focus on devastating big tech via Techno Anarchism. As usual, we aim to provide actionable content you can use to destroy...
カーソル追従オートズームで録画できるscreenkiteが良さげかも
macOS向け画面録画・動画編集アプリscreenkiteの紹介です。
Liminalia: allocation-free neural goal AI
Liminalia: neural network goal AI
Ctrl-Alt-Speech: Duty Of Careful What You Wish For
Ctrl-Alt-Speech is a weekly podcast about the latest news in online speech, from Mike Masnick and Everything in Moderation's Ben Whitelaw. Subscribe now on Apple Podcasts, Overcast, Spotify, Pocket Casts, YouTube, or your podcast app of choice — or go straight to the RSS feed. To get extended episodes with additional coverage, support us on...
„die wahrscheinliche wahrheit“
ich habs noch nicht zuende gelesen (erst 49%), aber ich kann das jetzt schion empfehlen: mads pankows buch: „die wahrscheinliche wahrheit“.
Letta Office Hours: Astra, Model Profiles, and Shared Memory
Astra and subscription setup, per-model context budgets, modern self-hosting, MemFS v2, shared skills, learning permissions, and the messaging gap around teleportation.
Leaked doc suggests Alberta has sprawling plans to pave the way for AI data centres, more oil production
Rewriting laws, creating Crown corporations that could rival TC Energy, building new natural gas pipelines and increasing prices for consumers: what a leaked document says about Alberta’s AI data centre and oil push
Two more newsrooms are suing OpenAI. It's complicated.
Publishers are suing AI vendors, accusing them of theft. But are they giving the creators responsible for building their value a fair deal?
Pook-Emu Bee: Links For 09-10-26
We went just over one week without daily Pook-Emu Bee links. Sickness (probably mostly allergies) and work intervened. But today I have a window for links. Back and better than ever? 1 | NCAA declares it cannot overturn outcome of game following Western Michigan's appeal (Daniel Hager for ON3. Sep. 9, 2026.) I didn't watch...
Automakers Pressure Congress To Ban Chinese EVs To ‘Protect Privacy’
If you enjoy badly written bipartisan protectionist tech legislation designed primarily to coddle giant U.S. companies under the xenophobia-tinged breathless pretense of privacy and national security, you are really going to enjoy the next twelve to twenty-four months.While the U.S. drowns in corrupt kakistocracy, the Chinese are making significant market inroads in everything from AI...
AIエージェントの計画を添削するPlannotatorが良さげかも
AIエージェントが出した計画や差分にブラウザから注釈を付けるPlannotatorの紹介です。
AI Agents Are Not Going “Rogue,” But Recent Developments Lead Increasingly-Concerned Researchers To Call For AI Slow Down
For the last few months, there has been much talk of AI agents going “rogue”. This is another of those unhelpful anthropomorphisms that are great for clickbait headlines, but which obscure a multitude of important issues. So far, there have been three major incidents of AI agents evading containment in their software “sandboxes” and going...
Persistent memory in Vercel eve
How eve carries saved preferences between conversations through scoped providers, recall messages, and memory tools.
OpenAI published its proof. Navier–Stokes is not settled yet.
The Lean code makes OpenAI’s claim inspectable. Machine checking, expert review, prize recognition, and provenance remain separate.
Fake Consumer Group Using AI To Generate Fake Support For Paramount Merger
In addition to the $111 billion Paramount/Warner Bros merger just being foundationally bad for creatives, labor, and consumers, the Ellison family-owned company's executives just keep demonstrating why they're not really the kind of folks you want dominating the lion's share of U.S. media.That's included calling deal critics "antisemitic," cozying up to foreign authoritarians, constantly threatening...
Job-Advice
Wenn Ihr dauerhaft mehrere #KI-Agenten gleichzeitig betreuen müsst: RENNT!
Mac用MarkdownエディタMarkViewerが良さげかも
編集も閲覧もエージェント呼び出しもできるMarkViewerの紹介です。
The cave has Wi-Fi now
What catches me in Angie Hobbs’s talk isn’t simply the claim that Plato anticipated fake news, demagogues and the slide from democracy into tyranny. Ancient philosophers are forever being advertised as having predicted the present. Give Marcus Aurelius a smartphone and he becomes a productivity guru. Give Plato an algorithm and suddenly the cave is...
The US Information Sector Payroll Slump May Not Be What You Thought
Everyone blames ChatGPT for information sector job losses. BLS payroll data on the information sector tells a very different story.
The DOJ’s AI Fair Use Brief Is Correct, But From A DOJ That Has No Credibility
I am never asking the monkey's paw for a federal government that defends fair use again. For decades on Techdirt, I've talked about the absolute necessity of strong fair use, and have been disappointed over and over again at how little the federal government has fought for fair use. For decades, the rare times when...
OpenAI's new model found zero-days. Most users get guarded access.
GPT-6 Astra crossed a Critical cyber threshold, but the launch separates the model's raw capability from what the public product permits.
Inbox-Free Verification, Browser Editors, and Direct DOM
This week explores inbox-free email verification and native spell-check dictionaries, compares browser editor and main-thread tradeoffs, and collects direct-DOM runtimes, a broader Remix, Rust-powered pnpm, and cheaper agent routing.
That is not dead which can eternal lie
Introducing WebDev Bench: A Coding-Agent Benchmark Judged on Web Platform Standards
WebDev Bench judges coding agents against the web platform's own standards, not visual fidelity or preference votes. Here is what the foundation phase built, what its first pilot found, and what comes next.
🐰
AI might tear the fabric of our society apart. But look at this bunny wearing a little hat!
AI research speeds up. Monitoring gets harder.
OpenAI says coding agents now run 3.1 days for every human research day, while its chief scientist warns the lab’s main monitoring method is weakening.
e567 — Infinite Pong World Model
e567 with Michael M and Andy - Stories and discussion on Xteink reader mods, PONG, mathematical innovations for dice, walled garden vs open vibe coding, World Models, AI productivity and a whole lot more!
PSA on RSSAmplifierBot and BriskBot
I discovered two new bots in my server logs last week: RSSAmplifierBot and BriskBot. They come from RSS Amplifier and Brisk News respectively. Bot sites are built by Profullstack, Inc. I discovered that RSS Amplifier, unbeknownst to me, had been crawling New Leaf Journal's ATOM feed and re-publishing (albeit they would not describe it as...
UPDATES, UPDATES
LUMVIEWER & TETHERNOTE
.plan-26-36: Ground control to major MODIS
Tessera v2 beta2 smooths space at the cost of time, new Pembroke Associate Scholars, Scrutineer's git remediation workflow, paying the Windows tax, and retiring AI disclosure metadata.
音声入力をローカルで完結させるMacParakeetが良さげかも
macOS上で完全ローカルに動作する音声入力・文字起こしアプリMacParakeetの紹介です。
Att Sverige har billig el är lockande för AI-företagen
Allt fler datacenter växer upp i Sverige. Bara en del av dem är dock till för AI, De flesta är för helt vanliga data, servrar för onlinetjänster och molntjänster av diverse slag. Det är i huvudsak US-amerikanska storföretag som Facebook, Amazon, Google och Microsoft som bygger dem.
The Programmer’s Fulcrum 4 September, 2026
Welcome to this week's The Programmer's Fulcrum. It's your weekly curation of the essential news in the Open Media Network and Open Social development communities with a focus on devastating big tech via Techno Anarchism. This post originally appeared on The Fulcrum. As usual, we aim to provide actionable content you can use to destroy...
PR review when everyone has LLMs
Ctrl-Alt-Speech: License To Spill
Ctrl-Alt-Speech is a weekly podcast about the latest news in online speech, from Mike Masnick and Everything in Moderation's Ben Whitelaw. Subscribe now on Apple Podcasts, Overcast, Spotify, Pocket Casts, YouTube, or your podcast app of choice — or go straight to the RSS feed. To get extended episodes with additional coverage, support us on...
Tom Cruise Parrots Paramount’s Empty Merger Promises Because He Loves His ‘Hollywood Family’
Just so we're clear: pre-merger promises (especially in the media and telecom sectors) are absolutely worthless. There's fifty years of indisputable evidence that all of the "synergies" and innovative improvements promised on the front end of major media mergers mean absolutely nothing. Especially in a country dead-set on defanging its labor and consumer protection regulators.To...
エージェントの足跡を3Dマップで再生するmindwalkが良さげかも
コーディングエージェントのセッションを3Dマップ上で再生するmindwalkの紹介です。
Love is for the ones who love the work.
Taking the final line of Joseph Fasano's poem 'For a Student Who Used AI to Write a Paper' as a starting point, I argue that loving the verb of creation matters more than daydreaming the noun. There's a wide chasm between writing discipline and the seduction of genAI shortcuts. The only way forward is to start doing the work—badly, bravely, and now.
MacアプリにくっつくAIサイドバーのSideKickが良さげかも
Macの任意のアプリにAIサイドバーを追加するSideKickの紹介です。
Letta Office Hours: MCP Tool Search, Teleportation, Cloud Files, and Agent Interfaces
Semantic MCP tool discovery, agent teleportation, Cloud Files, stateless queries, Agent SDK orchestration, cross-harness design, and interfaces that preserve human attention.
Letta Code 0.31.4–0.31.12
A technical account of the memory, remote execution, MCP, subagent, and runtime changes released between Letta Code 0.31.4 and 0.31.12.
Meta's best Muse score comes from a mode still in testing
Muse Spark 1.3 is live and independently competitive, but Meta's comparison table uses max reasoning—the mode it has not yet released.
Why your prompt cache hit rate is zero: the silent invalidators
Prompt caching is a prefix match: one changing byte near the top of your prompt drops your hit rate to zero. A timestamp is the obvious culprit - here are the rest.
Pook-Emu Bee: Links For 09-02-26
My throat is irrtated, my nose is stuffy, and I have a slight headache. It's ragweed season. Unrelated: It's time for our daily Pook-Emu Bee links. [caption id="attachment_7546" align="aligncenter" width="1008"] I took this photo in what I think was Cobble Hill on the afternoon of August 23, 2026.[/caption] 1 | Dating App Adds Feature Allowing...
Anthropic and Perplexity want less private data in their clouds
Anthropic is moving monitoring logs into customer-controlled cloud storage while Perplexity routes sensitive work to a Mac. Both reduce provider custody without eliminating trust in automated controls.